INFORMATION TRAINING SYSTEM FOR DISTANCE LEARNING THE METHODOLOGY FOR CARRYING OUT A MICRONUCLEAR TEST IN A HUMAN BUCKLE EPITELIUM

UDC 576.08:575.224
doi:10.26102/2310-6018/2019.25.2.012

V.N. Kalaev, M.S. Nechaeva, A.Y. Vasilyeva, I.Y. Vasilyev,
A.P. Preobrazhenskiy, I.Y. Lvovich


Informational training system contains visual, generalized, structured material on micronuclear analysis of human buccal epithelium cells: the history of the development of method, methodology, description of objects of analysis, photos of nuclear anomalies, list of factors affecting the genetic apparatus, materials for interactive assessment of learning outcomes. The informational training system allows to the researcher to quickly and visually get acquainted with the methodology of the micronucleus test, learn how to analyze microscopic preparations, find and correctly determine the anomalies of the nucleus of epithelial cells, carry out statistical processing of the results obtained and at the end of mastering the technique to evaluate the skills obtained through interactive testing. This information system summarizes the results of Russian and international studies on the assessment of the genetic homeostasis of the human organism using micronucleus test in the buccal epithelium, thereby contributing to the development of a standardized methodology and unifying approaches to describing the results of experiments to avoid incorrect interpretation of the data. The information system presents training video demonstrating the collection of material, preparation of micropreparations, basic equipment and reagents used in the performance of micronuclear analysis. The information system promotes the introduction of the micronucleus test in the human buccal epithelium as a routine procedure in clinical practice, monitoring of the environment, assessment of occupational risks, and allows for the development of measures to assess human genetic safety.

Keywords: :database, micronucleus test, human buccal epithelium, anomalies of the nucleus, epithelial cells of the oral cavity

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